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1-Azido-4,7,10-trioxa-13-tridecanamine

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Category Small-molecule Heterobifunctional PEG
Catalog NO. BPG-1823
Product Name 1-Azido-4,7,10-trioxa-13-tridecanamine
CAS 1162336-72-2
Molecular Formula C10H22N4O3
Molecular Weight 246.30
1-Azido-4,7,10-trioxa-13-tridecanamine
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Description 1-Azido-4,7,10-trioxa-13-tridecanamine is an azido-functionalized, polyether-based compound frequently utilized in bioorthogonal chemistry. Its terminal azide group participates efficiently in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions, facilitating site-specific conjugation and labeling of biomolecules. The flexible, hydrophilic backbone, derived from repeating ethylene glycol units, enhances solubility and molecular accessibility. Researchers employ this reagent extensively in peptide engineering, therapeutic delivery systems, and protein modification strategies.
Synonyms 1-Amino-11-azido-3,6,9-trioxaundecane; N3-TOTA; 3-[2-[2-(3-Azidopropoxy)ethoxy]ethoxy]propan-1-amine
IUPAC Name 3-[2-[2-(3-azidopropoxy)ethoxy]ethoxy]propan-1-amine
SMILES C(CN)COCCOCCOCCCN=[N+]=[N-]
InChI InChI=1S/C10H22N4O3/c11-3-1-5-15-7-9-17-10-8-16-6-2-4-13-14-12/h1-11H2
InChIKey VJXPLUVBIHOQFJ-UHFFFAOYSA-N
Boiling Point 198-202°C
Purity ≥ 98% (TLC)
Density 1.10 g/mL at 20 °C(lit.)
Appearance Light yellow oil
Storage Store at 2-8 °C

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