17:0-16:1 PC-[d5]

Name: 17:0-16:1 PC-[d5]
Brand: BOC Sciences
Rating: 5 (1 reviews)

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Category	Standards
Catalog NO.	BPG-3179
Product Name	17:0-16:1 PC-[d5]
CAS	2342575-79-3
Molecular Formula	C41H75D5NO8P
Molecular Weight	751.09

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Synonyms	1-heptadecanoyl-2-palmitoleoyl-sn-glycero(d5)-3-phosphocholine; 17:0-16:1 PC-d5; PC 17:0-16:1-d5; PC(17:0/16:1(9Z))-d5; 1-heptadecanoyl-2-(9Z-hexadecenoyl)-glycero-3-phosphocholine-d5
IUPAC Name	[(2R)-1,1,2,3,3-pentadeuterio-3-heptadecanoyloxy-2-[(Z)-hexadec-9-enoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate
SMILES	CCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCC
InChI	InChI=1S/C41H80NO8P/c1-6-8-10-12-14-16-18-20-22-23-25-27-29-31-33-40(43)47-37-39(38-49-51(45,46)48-36-35-42(3,4)5)50-41(44)34-32-30-28-26-24-21-19-17-15-13-11-9-7-2/h17,19,39H,6-16,18,20-38H2,1-5H3/b19-17-/t39-/m1/s1/i37D2,38D2,39D
InChIKey	DISVYZNGGMDUPX-FEZSZEOVSA-N
Purity	>99%
Solubility	Soluble in DCM, Methanol
Appearance	Liquid
Shelf Life	1 Year
Storage	Store at -20°C
Exact Mass	750.59
Hygroscopic	No
Light Sensitive	No
Percent Composition	C 65.56%, H 11.41%, N 1.86%, O 17.04%, P 4.12%

17:0-16:1 PC-[d5] is a deuterated phospholipid commonly used in lipidomics and other biochemical research. Here are some key applications of 17:0-16:1 PC-[d5]:

Lipidomics Research: In lipidomics studies, 17:0-16:1 PC-[d5] is used as an internal standard for precise quantification of lipid species in biological samples. Its deuterated nature allows for easy differentiation from naturally occurring lipids in mass spectrometry analyses. This aids in accurate profiling of lipid compositions in various tissues, fluids, and cells.

Membrane Structure and Function Studies: The unique properties of 17:0-16:1 PC-[d5] make it valuable for studying membrane dynamics and lipid-protein interactions. Researchers can incorporate it into artificial lipid bilayers to observe its impact on membrane properties, such as fluidity and phase behavior. This can provide insights into the biological functions of lipid membranes and their role in cellular processes.

Pharmacokinetics and Drug Delivery: 17:0-16:1 PC-[d5] can be utilized to investigate the pharmacokinetics of lipid-based drug delivery systems. By tracking the behavior of this deuterated phospholipid in the body, researchers can understand the distribution, metabolism, and clearance of lipid nanoparticles or liposomal formulations. This information is crucial for optimizing drug delivery strategies and improving therapeutic efficacy.

Stable Isotope Labeling Studies: The deuterium labels in 17:0-16:1 PC-[d5] make it an excellent tool for stable isotope labeling experiments. It can be incorporated into metabolic studies to trace lipid biosynthesis and turnover in living organisms. This application is essential for elucidating metabolic pathways and understanding lipid metabolism in health and disease contexts.

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