3,6,9,12,15-Pentaoxaoctadec-17-yn-1-ol
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| Category | Propargyl-PEGn-alcohol |
| Catalog NO. | BPG-1871 |
| Product Name | 3,6,9,12,15-Pentaoxaoctadec-17-yn-1-ol |
| CAS | 1036204-60-0 |
| Molecular Formula | C13H24O6 |
| Molecular Weight | 276.33 |
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Product Information
| Description | 3,6,9,12,15-Pentaoxaoctadec-17-yn-1-ol is a polyethylene glycol (PEG)-based PROTAC linker that can be used in the synthesis of a series of PROTACs. |
| Synonyms | Propargyl-PEG5-OH; Propargyl-PEG6-alcohol; Propyne-PEG5-OH; Alkyne-PEG5-OH; 2-[2-[2-[2-[2-(Propargyloxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanol |
| IUPAC Name | 2-[2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]ethoxy]ethanol |
| SMILES | C#CCOCCOCCOCCOCCOCCO |
| InChI | InChI=1S/C13H24O6/c1-2-4-15-6-8-17-10-12-19-13-11-18-9-7-16-5-3-14/h1,14H,3-13H2 |
| InChIKey | IDULHQAZDNBPID-UHFFFAOYSA-N |
| Boiling Point | 368.1±37.0 °C at 760 mmHg |
| Purity | >95% |
| Density | 1.078±0.06 g/cm3 (Predicted) |
| Solubility | Soluble in DCM, DMF, DMSO |
| Related CAS | 32199-97-6 (polymer) |
| Appearance | Pale Yellow Oily Liquid |
| Application | Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. Alkyne-PEG5-OH (Propargyl-PEG5-alcohol) is a PEG derivative containing a hydroxyl group and a propargyl group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. |
| Storage | Store at 2-8°C |
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