Acid-PEG7-NHS ester
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| Category | Acid-PEGn-NHS ester |
| Catalog NO. | BPG-1028 |
| Product Name | Acid-PEG7-NHS ester |
| Molecular Formula | C22H37NO13 |
| Molecular Weight | 523.53 |
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Product Information
| Description | Acid-PEG7-NHS ester is a PEG linker containing a carboxylic acid and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. |
| Synonyms | Acid-C2-PEG7-NHS ester; COOH-PEG7-SPA; COOH-PEG7-NHS; 25-((2,5-dioxopyrrolidin-1-yl)oxy)-25-oxo-4,7,10,13,16,19,22-heptaoxapentacosanoic acid |
| IUPAC Name | 3-[2-[2-[2-[2-[2-[2-[3-(2,5-dioxopyrrolidin-1-yl)oxy-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid |
| SMILES | O=C(O)CCOCCOCCOCCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O |
| InChI | InChI=1S/C22H37NO13/c24-19-1-2-20(25)23(19)36-22(28)4-6-30-8-10-32-12-14-34-16-18-35-17-15-33-13-11-31-9-7-29-5-3-21(26)27/h1-18H2,(H,26,27) |
| InChIKey | ODYMDPIFHPYYOH-UHFFFAOYSA-N |
| Purity | ≥95% |
| Related CAS | 1643594-31-3 (polymer) |
| Appearance | Light Yellow or White Solid |
| Storage | Store at 2-8°C |
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PEGylation of Peptides
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Reduce the Immunogenicity of Peptide/Protein Drugs
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Improved Circulation Half-Life
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