Aminooxy-PEG7-alcohol

Name: Aminooxy-PEG7-alcohol
Brand: BOC Sciences
Rating: 5 (1 reviews)

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Category	Aminooxy-PEGn-alcohol
Catalog NO.	BPG-0758
Product Name	Aminooxy-PEG7-alcohol
Molecular Formula	C14H31NO8
Molecular Weight	341.40

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Description	Aminooxy-PEG7-alcohol is a non-cleavable 7-unit PEG ADC linker that is used in the synthesis of antibody conjugated drugs (ADCs). Aminooxy-PEG7-alcohol is also a PROTAC linker, belonging to the PEG class, which can be used to synthesize PROTAC molecules.
Synonyms	20-(aminooxy)-3,6,9,12,15,18-hexaoxaicosan-1-ol
IUPAC Name	2-[2-[2-[2-[2-[2-(2-aminooxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
SMILES	C(COCCOCCOCCOCCOCCOCCON)O
InChI	InChI=1S/C14H31NO8/c15-23-14-13-22-12-11-21-10-9-20-8-7-19-6-5-18-4-3-17-2-1-16/h16H,1-15H2
InChIKey	WYWUBJZMXIFFBD-UHFFFAOYSA-N
Purity	≥95%
Appearance	Pale Yellow or Colorless Oily Matter
Storage	Store at 2-8°C

Aminooxy-PEG7-alcohol, a versatile compound widely utilized in biochemical research and various applications, demonstrates a diverse array of uses. Here are four key applications presented with high perplexity and burstiness:

Bioconjugation: Playing a pivotal role in bioconjugation methodologies, Aminooxy-PEG7-alcohol is extensively employed in linking biomolecules, such as proteins and peptides, through oxime ligation. This method provides a stable and efficient approach to connecting diverse molecules, facilitating the creation of bioconjugates used for diagnostic and therapeutic purposes. The integration of the PEG linker not only enhances solubility but also alleviates steric hindrance, ultimately boosting the efficacy of the conjugation process.

Drug Delivery Systems: In the realm of drug delivery, Aminooxy-PEG7-alcohol serves as a critical functional linker for constructing sophisticated drug conjugates and delivery vehicles. By binding to drug molecules or targeting ligands, it ensures precise delivery to specific tissues or cells. The process of PEGylation extends circulation time and decreases immunogenicity, ultimately enhancing the therapeutic effectiveness of the drug and optimizing treatment outcomes.

Surface Modification: Playing a crucial role in surface modification applications involving nanomaterials, biomaterials, and medical devices, Aminooxy-PEG7-alcohol aims to enhance biocompatibility and functionality. This compound facilitates the development of hydrophilic surfaces resistant to proteins, reducing nonspecific binding and improving overall performance. Such modifications are essential for the advancement of biosensors, implants, and other medical devices, elevating standards in healthcare technology.

Chemical Biology Research: Within the field of chemical biology, Aminooxy-PEG7-alcohol emerges as a key component in labeling and tracking biomolecules within complex biological systems. By attaching fluorescent dyes and other tags, researchers gain the ability to visualize and analyze biomolecular interactions in real-time, offering valuable insights into cellular processes and molecular dynamics.

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Why BOC Sciences?

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More than 2000+ products in inventory
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Multi specification for academic research and industrial production
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BOC Sciences supplies a unique variety of PEG derivatives and functional PEG polymers. Our products offer the most diverse collection of reactivity, ready-to-use functionality, and molecular weight options that you will not find anywhere else.