Azido-PEG12-hydrazide-Boc

Name: Azido-PEG12-hydrazide-Boc
Brand: BOC Sciences
Rating: 5 (1 reviews)

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Category	Azido-PEGn-hydrazide-Boc
Catalog NO.	BPG-0014
Product Name	Azido-PEG12-hydrazide-Boc
Molecular Formula	C32H63N5O15
Molecular Weight	757.88

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Description	Azido-PEG12-hydrazide-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Synonyms	Azido-PEG12-t-Boc-Hydrazide; tert-butyl 42-azido-4-oxo-7,10,13,16,19,22,25,28,31,34,37,40-dodecaoxa-2,3-diazadotetracontanoate
IUPAC Name	tert-butyl N-[3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoylamino]carbamate
SMILES	O=C(OC(C)(C)C)NNC(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])=O
InChI	InChI=1S/C32H63N5O15/c1-32(2,3)52-31(39)36-35-30(38)4-6-40-8-10-42-12-14-44-16-18-46-20-22-48-24-26-50-28-29-51-27-25-49-23-21-47-19-17-45-15-13-43-11-9-41-7-5-34-37-33/h4-29H2,1-3H3,(H,35,38)(H,36,39)
InChIKey	YYSCDAKZBRRCKI-UHFFFAOYSA-N
Purity	≥95%
Storage	Store at 2-8°C

Azido-PEG12-hydrazide-Boc, a versatile chemical reagent, finds its place in diverse bioconjugation and cross-linking endeavors. Here are four key applications of this compound, presented with a high degree of perplexity and burstiness:

Protein-Protein Cross-Linking: Delving into the realm of protein interactions, Azido-PEG12-hydrazide-Boc emerges as a pivotal player in protein cross-linking endeavors. By binding to specific protein sites, it orchestrates the creation of stable protein-protein conjugates, shedding light on protein functions and dynamics within intricate biological landscapes.

Drug Delivery Systems: At the forefront of drug delivery innovation, Azido-PEG12-hydrazide-Boc takes center stage in crafting targeted and efficient drug delivery systems. Its prowess in forming steadfast conjugates with drugs and targeting ligands enables precise delivery to desired cellular destinations, amplifying therapeutic efficacy while minimizing off-target repercussions.

Surface Modification: Unveiling its utility in surface modification terrain, this reagent proves indispensable for enhancing nanoparticles, biosensors, and medical devices. By furnishing functional groups for subsequent conjugation, it facilitates the attachment of bioactive molecules like antibodies, peptides, or nucleic acids to surfaces, ushering in a new era of biofunctional surfaces poised to elevate performance benchmarks in diagnostics and therapeutic realms.

Chemical Biology Research: In the intricate domain of chemical biology, Azido-PEG12-hydrazide-Boc takes on a pivotal role in introducing azide groups into biomolecules for click chemistry reactions. This strategic maneuver fuels investigations into biomolecular interactions, pathways, and functions, serving as an essential ally in labeling, tracking, and manipulating biomolecules amidst the complexities of biological milieus.

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BOC Sciences supplies a unique variety of PEG derivatives and functional PEG polymers. Our products offer the most diverse collection of reactivity, ready-to-use functionality, and molecular weight options that you will not find anywhere else.