Bis-PEG9-acid
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| Category | COOH-PEGn-COOH |
| Catalog NO. | BPG-2283 |
| Product Name | Bis-PEG9-acid |
| CAS | 1268488-70-5 |
| Molecular Formula | C22H42O13 |
| Molecular Weight | 514.56 |
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Product Information
| Description | Bis-PEG9-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Bis-PEG9-acid is also a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| Synonyms | 4,7,10,13,16,19,22,25,28-Nonaoxahentriacontanedioic acid; HOOC-PEG9-COOH; HOOCCH2CH2O-PEG8-CH2CH2COOH; α,ω-dipropionic acid octaethylene glycol; 4,7,10,13,16,19,22,25,28-Nonaoxahentriacontane-1,31-dioic acid |
| IUPAC Name | 3-[2-[2-[2-[2-[2-[2-[2-[2-(2-carboxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid |
| SMILES | C(COCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)O)C(=O)O |
| InChI | InChI=1S/C22H42O13/c23-21(24)1-3-27-5-7-29-9-11-31-13-15-33-17-19-35-20-18-34-16-14-32-12-10-30-8-6-28-4-2-22(25)26/h1-20H2,(H,23,24)(H,25,26) |
| InChIKey | MZPXCHJGEDEJHQ-UHFFFAOYSA-N |
| Boiling Point | 630.0±55.0 °C at 760 mmHg |
| Flash Point | 201.6±25.0 °C |
| Purity | ≥95% |
| Density | 1.174±0.06 g/cm3 (Predicted) |
| Solubility | Soluble in DMSO (10 mm) |
| Related CAS | 51178-68-8 (polymer) |
| Appearance | Pale Yellow or Colorless Oily Matter |
| Storage | Store at 2-8°C |
| Exact Mass | 514.26254139 |
| Vapor Pressure | 0.0±4.0 mmHg at 25°C |
| LogP | -3.33 |
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PEGylation of Peptides
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Reduce the Immunogenicity of Peptide/Protein Drugs
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