C15 Ceramide (d18:1/15:0)

Name: C15 Ceramide (d18:1/15:0)
Brand: BOC Sciences
Rating: 5 (1 reviews)

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Category	Bile Acid Standards
Catalog NO.	BPG-3153
Product Name	C15 Ceramide (d18:1/15:0)
CAS	67492-15-3
Molecular Formula	C33H65NO3
Molecular Weight	523.87

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Description	C15 Ceramide (d18:1/15:0) is a naturally occurring ceramide that has been found in L. nidifica and A. glomerata extracts, human erythrocytes, and the stratum corneum of P. domesticus. Ceramide plays a key role in the anabolic and catabolic pathways of sphingolipids. It acts as an extracellular stimuli for many cellular processes like differentiation, growth suppression, cell senescence and apoptosis.
Synonyms	N-(pentadecanoyl)-4E-sphingenine; N-pentadecanoyl-D-erythro-sphingosine; Cer(d18:1(4E)/15:0); C15 D-erythro Ceramide (d18:1/15:0)
IUPAC Name	N-[(E,2S,3R)-1,3-dihydroxyoctadec-4-en-2-yl]pentadecanamide
SMILES	CCCCCCCCCCCCCCC(=O)NC(CO)C(C=CCCCCCCCCCCCCC)O
InChI	InChI=1S/C33H65NO3/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-32(36)31(30-35)34-33(37)29-27-25-23-21-19-16-14-12-10-8-6-4-2/h26,28,31-32,35-36H,3-25,27,29-30H2,1-2H3,(H,34,37)/b28-26+/t31-,32+/m0/s1
InChIKey	HBULQAPKKLNTLT-STSAHMJASA-N
Purity	>99%
Shelf Life	1 Year
Storage	Store at -20°C
Exact Mass	523.5
Hygroscopic	No
Light Sensitive	No
Percent Composition	C 75.66%, H 12.51%, N 2.67%, O 9.16%

C15 Ceramide (d18:1/15:0) is widely regarded for its pivotal role in dermatological applications, particularly in skincare products aimed at enhancing barrier function. The molecule's ability to repair and reinforce the skin's natural barrier is essential for individuals with conditions such as eczema and psoriasis. By integrating C15 Ceramide into moisturizers and topical treatments, manufacturers address common issues like dehydration, irritation, and sensitivity. This biochemical marvel restores the lipid structure in the stratum corneum, leading to improved skin hydration and resilience. Such properties make it a star ingredient in high-performance skincare formulations focused on barrier repair and maintenance.

Beyond skincare, C15 Ceramide (d18:1/15:0) holds promise in the field of neurobiology. Ceramides play a crucial role in neuronal signaling and brain health, with particular emphasis on their involvement in cell signaling pathways related to growth, differentiation, and apoptosis. Research into ceramide's impact on neurodegenerative diseases like Alzheimer's and Parkinson's is burgeoning. By modulating ceramide levels in neural tissues, scientists aim to decipher new therapeutic strategies that could slow or even reverse disease progression, offering hope for enhanced cognitive function and neuroprotection.

In oncology, C15 Ceramide (d18:1/15:0) is investigated for its potential anti-cancer properties. Ceramide is known to induce apoptosis in cancer cells, making it a focal point for developing novel treatments. Researchers explore how manipulating ceramide metabolism or mimicking its effects can potentially starve tumors of their proliferative capabilities. By understanding and harnessing ceramide's apoptotic pathways, new chemotherapeutic agents aim not only to kill cancer cells more efficiently but to reduce the side effects compared to traditional treatments. The specificity and potency of C15 Ceramide in triggering cancer cell death present a promising avenue for future anti-cancer therapies.

Lastly, C15 Ceramide (d18:1/15:0) finds crucial applications in the area of metabolic diseases, including diabetes and obesity. Ceramides are implicated in the regulation of insulin signaling and lipid metabolism. Elevated levels of certain ceramides are associated with insulin resistance and metabolic dysregulation. By targeting ceramide synthesis or its metabolic pathways, researchers hope to develop new interventions that improve insulin sensitivity and metabolic outcomes. Such advancements could lead to innovative treatments that better manage or even prevent metabolic syndrome, reducing the burden of these pervasive health challenges.

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