Fmoc-N-amido-PEG4-acetic acid
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| Category | Fmoc-NH-PEGn-CH2COOH |
| Catalog NO. | BPG-2219 |
| Product Name | Fmoc-N-amido-PEG4-acetic acid |
| CAS | 437655-95-3 |
| Molecular Formula | C25H31NO8 |
| Molecular Weight | 473.52 |
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Product Information
| Description | Fmoc-N-amido-PEG4-acetic acid is a PEG linker intermediate with an Fmoc protecting group, used for stepwise ADC linker synthesis. The PEG4 spacer improves hydrophilicity and flexibility, aiding in controlled payload conjugation and antibody modification. |
| Synonyms | Fmoc-NH-PEG4-CH2COOH; 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azaoctadecan-18-oic acid; 5,8,11,14-Tetraoxa-2-azahexadecanedioic acid; 5,8,11,14-Tetraoxa-2-azahexadecanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester; Fmoc-PEG4-acetic acid; 2,7,10,13,16-Pentaoxa-4-azaoctadecan-18-oic acid, 1-(9H-fluoren-9-yl)-3-oxo- |
| IUPAC Name | 2-[2-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid |
| SMILES | C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCOCCOCCOCCOCC(=O)O |
| InChI | InChI=1S/C25H31NO8/c27-24(28)18-33-16-15-32-14-13-31-12-11-30-10-9-26-25(29)34-17-23-21-7-3-1-5-19(21)20-6-2-4-8-22(20)23/h1-8,23H,9-18H2,(H,26,29)(H,27,28) |
| InChIKey | XPNLDOFYRFOXLR-UHFFFAOYSA-N |
| Boiling Point | 681.3±55.0°C (Predicted) |
| Melting Point | 51°C |
| Purity | ≥95% |
| Density | 1.235±0.06 g/cm3 (Predicted) |
| Solubility | Soluble in DMSO (10 mm) |
| Related CAS | 675606-79-8 (polymer) |
| Appearance | Pale Yellow or Colorless Oily Matter |
| Storage | Store at 2-8°C |
| Exact Mass | 473.20496695 |
| LogP | 2.88050 |
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