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Fmoc-N-amido-PEG4-acetic acid

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Category Fmoc-NH-PEGn-CH2COOH
Catalog NO. BPG-2219
Product Name Fmoc-N-amido-PEG4-acetic acid
CAS 437655-95-3
Molecular Formula C25H31NO8
Molecular Weight 473.52
Fmoc-N-amido-PEG4-acetic acid
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Description Fmoc-N-amido-PEG4-acetic acid is a PEG linker intermediate with an Fmoc protecting group, used for stepwise ADC linker synthesis. The PEG4 spacer improves hydrophilicity and flexibility, aiding in controlled payload conjugation and antibody modification.
Synonyms Fmoc-NH-PEG4-CH2COOH; 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azaoctadecan-18-oic acid; 5,8,11,14-Tetraoxa-2-azahexadecanedioic acid; 5,8,11,14-Tetraoxa-2-azahexadecanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester; Fmoc-PEG4-acetic acid; 2,7,10,13,16-Pentaoxa-4-azaoctadecan-18-oic acid, 1-(9H-fluoren-9-yl)-3-oxo-
IUPAC Name 2-[2-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid
SMILES C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCOCCOCCOCCOCC(=O)O
InChI InChI=1S/C25H31NO8/c27-24(28)18-33-16-15-32-14-13-31-12-11-30-10-9-26-25(29)34-17-23-21-7-3-1-5-19(21)20-6-2-4-8-22(20)23/h1-8,23H,9-18H2,(H,26,29)(H,27,28)
InChIKey XPNLDOFYRFOXLR-UHFFFAOYSA-N
Boiling Point 681.3±55.0°C (Predicted)
Melting Point 51°C
Purity ≥95%
Density 1.235±0.06 g/cm3 (Predicted)
Solubility Soluble in DMSO (10 mm)
Related CAS 675606-79-8 (polymer)
Appearance Pale Yellow or Colorless Oily Matter
Storage Store at 2-8°C
Exact Mass 473.20496695
LogP 2.88050

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