Hydroxy-PEG1-acid
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| Category | HO-PEGn-COOH |
| Catalog NO. | BPG-0643 |
| Product Name | Hydroxy-PEG1-acid |
| CAS | 89211-34-7 |
| Molecular Formula | C5H10O4 |
| Molecular Weight | 134.13 |
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Product Information
| Description | Hydroxy-PEG1-acid is a hydrophilic ADC linker intermediate with a short PEG1 spacer and terminal carboxyl group, enhancing solubility and enabling versatile conjugation in antibody-drug conjugates for improved payload stability and delivery. Keywords: ADC linker, PEG linker, hydrophilic spacer, payload conjugation, antibody-drug conjugate. |
| Synonyms | OH-PEG1-COOH; HO-PEG1-Propionic acid; HO-PEG1-CH2CH2COOH; Hydroxy-PEG1-propionic acid; 3-(2-hydroxyethoxy)propionic acid; Propanoic acid, 3-(2-hydroxyethoxy)- |
| IUPAC Name | 3-(2-hydroxyethoxy)propanoic acid |
| SMILES | C(COCCO)C(=O)O |
| InChI | InChI=1S/C5H10O4/c6-2-4-9-3-1-5(7)8/h6H,1-4H2,(H,7,8) |
| InChIKey | GTIFLSYPOXYYFG-UHFFFAOYSA-N |
| Boiling Point | 127-130°C at 2 Torr |
| Purity | ≥95% |
| Density | 1.224±0.06 g/cm3 (Predicted) |
| Solubility | Soluble in DMSO |
| Related CAS | 117786-94-4 |
| Appearance | Pale Yellow or Colorless Oily Matter |
| Shelf Life | 0-4°C for short term (days to weeks), or -20°C for long term (months). |
| Storage | Store at 2-8°C |
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BOC Sciences supplies a unique variety of PEG derivatives and functional PEG polymers. Our products offer the most diverse collection of reactivity, ready-to-use functionality, and molecular weight options that you will not find anywhere else.
PEGylation of Peptides
and Proteins
Reduce the Immunogenicity of Peptide/Protein Drugs
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APPLICATIONS
PEG linkers For Drug
Improved Circulation Half-Life
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