mPEG10-alcohol
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| Category | Small-molecule Methoxy Linear PEG (mPEG) |
| Catalog NO. | BPG-2218 |
| Product Name | mPEG10-alcohol |
| CAS | 27425-92-9 |
| Molecular Formula | C21H44O11 |
| Molecular Weight | 472.57 |
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Product Information
| Description | m-PEG10-alcohol (Decaethylene glycol monomethyl ether) is a non-cleavable 10 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG10-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
| Synonyms | Decaethylene Glycol Monomethyl Ether; mPEG10-OH; 2,5,8,11,14,17,20,23,26,29-Decaoxahentriacontan-31-ol |
| IUPAC Name | 2-[2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol |
| SMILES | COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO |
| InChI | InChI=1S/C21H44O11/c1-23-4-5-25-8-9-27-12-13-29-16-17-31-20-21-32-19-18-30-15-14-28-11-10-26-7-6-24-3-2-22/h22H,2-21H2,1H3 |
| InChIKey | YMBLPWKGRIGDBP-UHFFFAOYSA-N |
| Boiling Point | 524.316°C at 760 mmHg |
| Melting Point | 19°C |
| Flash Point | 270.9±28.7 °C |
| Purity | >98.0% |
| Density | 1.083g/cm3 |
| Solubility | 10 mm in DMSO |
| Appearance | Solid |
| Shelf Life | 0-4°C for short term (days to weeks), or -20°C for long term (months). |
| Storage | Store at -20 °C, keep in dry and avoid sunlight. |
| Vapor Pressure | 0.0±3.1 mmHg at 25°C |
| LogP | -4.02 |
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PEGylation of Peptides
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Reduce the Immunogenicity of Peptide/Protein Drugs
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