Propargyl-PEG6-acid
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| Category | Propargyl-PEGn-acid |
| Catalog NO. | BPG-2002 |
| Product Name | Propargyl-PEG6-acid |
| CAS | 1951438-84-8 |
| Molecular Formula | C16H28O8 |
| Molecular Weight | 348.39 |
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Product Information
| Description | Propargyl-PEG6-acid is a hydrophilic linker with an alkyne group for click chemistry and a carboxylic acid for conjugation. Used in ADC linker development to improve payload accessibility and aqueous solubility in therapeutic antibody conjugates. |
| Synonyms | Propyne-PEG5-CH2CH2COOH; Alkyne-PEG6-COOH; Propargyl-PEG6-COOH; Propargyl-PEG5-CH2CH2COOH; 4,7,10,13,16,19-Hexaoxadocos-21-yn-1-oic acid; 4,7,10,13,16,19-Hexaoxadocos-21-ynoic acid |
| IUPAC Name | 3-[2-[2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid |
| SMILES | C#CCOCCOCCOCCOCCOCCOCCC(=O)O |
| InChI | InChI=1S/C16H28O8/c1-2-4-19-6-8-21-10-12-23-14-15-24-13-11-22-9-7-20-5-3-16(17)18/h1H,3-15H2,(H,17,18) |
| InChIKey | XRSJYQQOJNYUDV-UHFFFAOYSA-N |
| Boiling Point | 462.8±45.0 °C at 760 mmHg |
| Flash Point | 157.6±22.2 °C |
| Purity | >98.0% |
| Density | 1.126±0.06 g/cm3 (Predicted) |
| Solubility | Soluble in DMSO, Water |
| Appearance | Pale Yellow or Colorless Oily Liquid |
| Shelf Life | ≥ 2 years |
| Storage | Store at 2-8°C |
| Vapor Pressure | 0.0±2.5 mmHg at 25°C |
| LogP | -1.52 |
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BOC Sciences supplies a unique variety of PEG derivatives and functional PEG polymers. Our products offer the most diverse collection of reactivity, ready-to-use functionality, and molecular weight options that you will not find anywhere else.
PEGylation of Peptides
and Proteins
Reduce the Immunogenicity of Peptide/Protein Drugs
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APPLICATIONS
PEG linkers For Drug
Improved Circulation Half-Life
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