t-Boc-N-amido-PEG1-propionic acid
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| Category | NHBoc-PEG-COOH |
| Catalog NO. | BPG-1801 |
| Product Name | t-Boc-N-amido-PEG1-propionic acid |
| CAS | 1260092-44-1 |
| Molecular Formula | C10H19NO5 |
| Molecular Weight | 233.26 |
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Product Information
| Description | t-Boc-N-amido-PEG1-propionic acid is a cleavable (1-unit PEG) ADC linker, as well as a PEG- and alkyl/ether-based PROTAC linker that can be used to synthesize antibody-drug conjugates (ADCs) or PROTACs. |
| Synonyms | t-Boc-N-amido-PEG1-acid; Boc-NH-PEG1-CH2CH2COOH; t-Boc-NH-amido-PEG1-COOH; Boc-NH-PEG1-COOH; 3-[2-(Boc-amino)ethoxy]propanoic Acid; 3-(2-N-Boc-aminoethoxy)propanoic acid; 3-(2-((tert-Butoxycarbonyl)amino)ethoxy)propanoic acid; Propanoic acid, 3-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-; 3-[2-({[(2-Methyl-2-propanyl)oxy]carbonyl}amino)ethoxy]propanoic acid |
| IUPAC Name | 3-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethoxy]propanoic acid |
| SMILES | CC(C)(C)OC(=O)NCCOCCC(=O)O |
| InChI | InChI=1S/C10H19NO5/c1-10(2,3)16-9(14)11-5-7-15-6-4-8(12)13/h4-7H2,1-3H3,(H,11,14)(H,12,13) |
| InChIKey | YGNSGMAPLOVGIU-UHFFFAOYSA-N |
| Boiling Point | 385.0±27.0 °C at 760 mmHg |
| Flash Point | 186.7±23.7 °C |
| Purity | ≥95% |
| Density | 1.127±0.06 g/cm3 (Predicted) |
| Solubility | Soluble in DMSO |
| Related CAS | 187848-68-6 (polymer) |
| Appearance | Pale Yellow or Colorless Oily Liquid |
| Storage | Store at 2-8°C |
| Exact Mass | 233.12632271 |
| Vapor Pressure | 0.0±1.9 mmHg at 25°C |
| LogP | 0.93 |
| Pictogram(s) | Irritant |
| Signal | Warning |
| Precautionary Statement Codes | P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 |
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