3A-MPLA
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
| Category | Adjuvants |
| Catalog NO. | BPG-3016 |
| Product Name | 3A-MPLA |
| CAS | 1699735-80-2 |
| Molecular Formula | C54H106N3O17P |
| Molecular Weight | 1100.40 |
- Scheme Design
- Custom Synthesis
- cGMP Manufacturing
- Quality Assurance
- Product Information
- Documents
- Reviews
Product Information
| Description | Monophosphoryl lipid A (MPLA) is an analog of the lipid A moiety. It is regarded as a detoxified derivative of the lipopolysaccharide (LPS). MPLA is a natural agonist for the toll-like receptor-4 (TLR4). MPLA is a safe prophylactic agent and has immunotherapeutic applications. It induces tumor necrosis factor and interleukin (IL)-1β, however not as efficient as lipopolysaccharide (LPS). MPLA improves immune response during bacterial sepsis infection. |
| Synonyms | Monophosphoryl Tri-acyl Lipid A |
| IUPAC Name | azanium;[(3S,5S,6R)-4-hydroxy-2-(hydroxymethyl)-5-[[(3R)-3-tetradecanoyloxytetradecanoyl]amino]-6-[[(3S,5S,6S)-3,4,6-trihydroxy-5-[[(3R)-3-hydroxytetradecanoyl]amino]oxan-2-yl]methoxy]oxan-3-yl] hydrogen phosphate |
| SMILES | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)NC1C(C(C(OC1OCC2C(C(C(C(O2)O)NC(=O)CC(CCCCCCCCCCC)O)O)O)CO)OP(=O)(O)[O-])O.[NH4+] |
| InChI | InChI=1S/C54H103N2O17P.H3N/c1-4-7-10-13-16-19-20-23-26-29-32-35-46(61)70-41(34-31-28-25-22-18-15-12-9-6-3)37-45(60)56-48-51(64)52(73-74(66,67)68)42(38-57)72-54(48)69-39-43-49(62)50(63)47(53(65)71-43)55-44(59)36-40(58)33-30-27-24-21-17-14-11-8-5-2;/h40-43,47-54,57-58,62-65H,4-39H2,1-3H3,(H,55,59)(H,56,60)(H2,66,67,68);1H3/t40-,41-,42?,43?,47+,48+,49-,50?,51?,52-,53+,54-;/m1./s1 |
| InChIKey | WBMOMCHVNLUEBA-UPPRWESDSA-N |
| Purity | >99% |
| Appearance | Powder |
| Shelf Life | 1 Year |
| Storage | Store at -20°C |
| Exact Mass | 1099.726 |
| Hygroscopic | No |
| Light Sensitive | No |
| Percent Composition | C 58.94%, H 9.71%, N 3.82%, O 24.72%, P 2.81% |
Reviews
If you have any suggestions or comments about 3A-MPLA , please submit a review immediately.
Why BOC Sciences?
-
Large Stock
More than 2000+ products in inventory
-
Global Delivery
Warehouses in multiple cities to ensure fast delivery
-
mg to kg
Multi specification for academic research and industrial production
-
24/7 Technical Support
Strict process parameter control to ensure product quality
Our Feature
BOC Sciences supplies a unique variety of PEG derivatives and functional PEG polymers. Our products offer the most diverse collection of reactivity, ready-to-use functionality, and molecular weight options that you will not find anywhere else.
PEGylation of Peptides
and Proteins
Reduce the Immunogenicity of Peptide/Protein Drugs
Learn More
APPLICATIONS
PEG linkers For Drug
Improved Circulation Half-Life
Learn More
Have Customer
Reviewed On Us?
Chat With Us
