Amino-PEG12-amine

Name: Amino-PEG12-amine
Brand: BOC Sciences
Rating: 5 (1 reviews)

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Category	Amino-PEGn-amine
Catalog NO.	BPG-0684
Product Name	Amino-PEG12-amine
CAS	361543-12-6
Molecular Formula	C26H56N2O12
Molecular Weight	588.74

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Description	Amino-PEG12-amine is a homobifunctional PEG linker containing two amino groups, which can react with carboxylic acids, activated NHS esters, carbonyls and so on.
Synonyms	H2N-PEG12-CH2CH2NH2; 1,38-Diamino-3,6,9,12,15,18,21,24,27,30,33,36-dodecaoxaoctatriacontane; 3,6,9,12,15,18,21,24,27,30,33,36-Dodecaoxaoctatriacontane-1,38-diamine
IUPAC Name	2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanamine
SMILES	C(COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN)N
InChI	InChI=1S/C26H56N2O12/c27-1-3-29-5-7-31-9-11-33-13-15-35-17-19-37-21-23-39-25-26-40-24-22-38-20-18-36-16-14-34-12-10-32-8-6-30-4-2-28/h1-28H2
InChIKey	LBBOTXXNKBSUJN-UHFFFAOYSA-N
Boiling Point	621.3±50.0°C at 760 mmHg
Purity	≥95%
Density	1.087±0.06 g/cm3 at 20°C, 760 Torr
Appearance	Colorless Oily Matter
Storage	Store at 2-8°C

A versatile compound with wide-ranging applications in bioscience and related fields, Amino-PEG12-amine is at the forefront of scientific innovation. Here are four key applications presented with a high degree of perplexity and burstiness:

Bioconjugation: A cornerstone of modern biotechnology, Amino-PEG12-amine plays a pivotal role in bioconjugation techniques, facilitating the linking of biomolecules like proteins, peptides, and antibodies to diverse surfaces or molecules. Its PEG spacer, known for its flexibility and ability to reduce steric hindrance, elevates the stability and solubility of conjugates, thus revolutionizing the creation of cutting-edge diagnostic tools and therapeutic agents with enhanced effectiveness.

Drug Delivery Systems: In the realm of drug delivery systems, Amino-PEG12-amine emerges as a game-changer, instrumental in the functionalization of nanoparticles and other delivery vehicles. The process of PEGylation not only enhances the pharmacokinetics of drugs, prolonging their circulation time and reducing immunogenicity, but also optimizes targeted drug delivery, amplifying treatment efficacy while mitigating unwanted side effects, marking a significant leap in medical progress.

Surface Modification: Delving into the domain of surface modification, Amino-PEG12-amine showcases its prowess in enhancing medical devices and biomaterials. By bonding to surfaces, it engenders a biocompatible layer capable of repelling protein adsorption and cell adhesion, thus diminishing infection risks and fostering superior integration of implants.

Protein Purification: An indispensable tool in protein purification protocols, Amino-PEG12-amine takes center stage in creating affinity tags that streamline the selective binding and isolation of target proteins. Leveraging the PEG linker to minimize non-specific interactions and bolster the solubility and stability of tagged proteins, this method yields proteins of unparalleled purity and yield, essential components for diverse biochemical and structural studies that pave the way for groundbreaking scientific insights.

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