Cbz-N-amido-PEG3-acid

Name: Cbz-N-amido-PEG3-acid
Brand: BOC Sciences
Rating: 5 (1 reviews)

* Please be kindly noted products are not for therapeutic use. We do not sell to patients.

Category	Small-molecule Group Protected PEG
Catalog NO.	BPG-2015
Product Name	Cbz-N-amido-PEG3-acid
CAS	1310327-18-4
Molecular Formula	C₁₇H₂₅NO₇
Molecular Weight	355.38

Scheme Design
Custom Synthesis
cGMP Manufacturing
Quality Assurance

Product Information
Application
Documents
Reviews

Product Information

Description	Cbz-NH-PEG3-C2-acid is a polyethylene glycol (PEG)-based PROTAC linker. Cbz-NH-PEG3-C2-acid can be used in the synthesis of a series of PROTACs.
Synonyms	Cbz-12-amino-4,7,10-trioxadodecanoic acid; CBZ-AEEEP; Cbz-NH-PEG3-CH2CH2COOH; Cbz-NH-PEG3-propionic acid
IUPAC Name	3-[2-[2-[2-(phenylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]propanoic acid
SMILES	C1=CC=C(C=C1)COC(=O)NCCOCCOCCOCCC(=O)O
InChI	InChI=1S/C17H25NO7/c19-16(20)6-8-22-10-12-24-13-11-23-9-7-18-17(21)25-14-15-4-2-1-3-5-15/h1-5H,6-14H2,(H,18,21)(H,19,20)
InChIKey	SBHUTZVKPJPFBD-UHFFFAOYSA-N
Purity	>98%
Appearance	Viscous Liquid
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.

Cbz-N-amido-PEG3-acid, a versatile chemical compound with diverse applications in bioscience and chemical research, showcases its utility in various domains. Embracing high perplexity and burstiness, here are four key applications:

Peptide Synthesis: In the intricate world of peptide synthesis, Cbz-N-amido-PEG3-acid shines as a crucial component, acting as a linker or spacer in elongating peptide chains. The PEG3 segment, composed of polyethylene glycol, plays a pivotal role in enhancing solubility and reducing peptide aggregation. This enhancement facilitates seamless coupling reactions, resulting in higher yields of the desired peptides, accentuating the efficiency of the synthesis process.

Drug Delivery Systems: At the forefront of pharmaceutical research, Cbz-N-amido-PEG3-acid emerges as a game-changer in enhancing drug delivery systems. PEGylation, the attachment of PEG chains, serves to boost the solubility, stability, and bioavailability of therapeutic agents. This modification leads to prolonged circulation time within the body, amplifying the efficacy of drugs and potentially revolutionizing the realm of drug delivery.

Bioconjugation: Delving into bioconjugation techniques, Cbz-N-amido-PEG3-acid plays a crucial role in linking biomolecules like proteins, antibodies, or nucleic acids to other functional molecules or surfaces. The presence of the PEG3 spacer ensures flexibility and reduces steric hindrance, facilitating efficient conjugation while preserving the biological activity of the molecules. This application holds significant importance in diagnostics, imaging, and therapeutic targeting, showcasing the versatility and adaptability of Cbz-N-amido-PEG3-acid.

Polymer Chemistry: Within the realm of polymer science, Cbz-N-amido-PEG3-acid stands out as a foundational building block for creating functionalized polymers. By incorporating this compound into polymer backbones, specific chemical functionalities such as carboxyl or amine groups can be introduced, allowing for the customization of polymers with tailored properties. These custom polymers find applications in diverse fields, including drug delivery, tissue engineering, and other biomedical endeavors, adding a layer of complexity and sophistication to polymer chemistry.

Documents

SDS
COAs

Reviews

If you have any suggestions or comments about Cbz-N-amido-PEG3-acid , please submit a review immediately.