DBCO-NH-PEG4-maleimide
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| Category | Small-molecule Heterobifunctional PEG |
| Catalog NO. | BPG-2467 |
| Product Name | DBCO-NH-PEG4-maleimide |
| CAS | 1480516-75-3 |
| Molecular Formula | C36H42N4O9 |
| Molecular Weight | 674.74 |
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Product Information
| Description | DBCO-NH-PEG4-maleimide is a heterobifunctional ADC linker combining maleimide thiol-reactivity and DBCO for SPAAC click chemistry, facilitating versatile and stable antibody-drug conjugate formation. |
| Synonyms | DBCO-PEG4-Maleimide;DBCO-NH-PEG4-Maleimide; DBCO-PEG4-MAL |
| IUPAC Name | N-[2-[2-[2-[2-[3-[[3-(2-azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl)-3-oxopropyl]amino]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethyl]-3-(2,5-dioxopyrrol-1-yl)propanamide |
| SMILES | C1C2=CC=CC=C2C#CC3=CC=CC=C3N1C(=O)CCNC(=O)CCOCCOCCOCCOCCNC(=O)CCN4C(=O)C=CC4=O |
| InChI | InChI=1S/C36H42N4O9/c41-32(14-18-39-34(43)11-12-35(39)44)38-17-20-47-22-24-49-26-25-48-23-21-46-19-15-33(42)37-16-13-36(45)40-27-30-7-2-1-5-28(30)9-10-29-6-3-4-8-31(29)40/h1-8,11-12H,13-27H2,(H,37,42)(H,38,41) |
| InChIKey | VVFZXPZWVJMYPX-UHFFFAOYSA-N |
| Boiling Point | 965.2±65.0 °C at 760 mmHg |
| Flash Point | 537.6±34.3 °C |
| Purity | >98.0% |
| Density | 1.3±0.1 g/cm3 |
| Solubility | 10 mm in DMSO |
| Appearance | Solid |
| Shelf Life | -20°C 3 years powder; -80°C 2 years in solvent |
| Storage | Store at -20 °C, keep in dry and avoid sunlight. |
| Vapor Pressure | 0.0±0.3 mmHg at 25°C |
| LogP | 1.22 |
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BOC Sciences supplies a unique variety of PEG derivatives and functional PEG polymers. Our products offer the most diverse collection of reactivity, ready-to-use functionality, and molecular weight options that you will not find anywhere else.
PEGylation of Peptides
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Reduce the Immunogenicity of Peptide/Protein Drugs
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