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DOPE-PEG-COOH sodium salt

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Category mPEG Phospholipids
Catalog NO. BPG-3000
Product Name DOPE-PEG-COOH sodium salt
CAS 2342575-87-3
Molecular Formula (C2H4O)nC45H82NO12P.Na
Molecular Weight 2776.381
DOPE-PEG-COOH sodium salt
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Description DOPE-PEG-COOH sodium salt contains a terminal carboxyl group on a PEGylated DOPE scaffold, enabling covalent attachment of amine-containing biomolecules via carbodiimide chemistry. The hydrophilic PEG spacer ensures accessibility and minimizes nonspecific adsorption, while the DOPE moiety promotes stable bilayer insertion and curvature modulation. This functional lipid is widely applied in customizing liposome surfaces, preparing bioresponsive membrane constructs, and engineering lipid–polymer hybrid systems. Its sodium salt form enhances solubility and handling in aqueous formulations, making it ideal for precision surface chemistry and biomimetic nanomaterial development.
Synonyms DOPE-PEG-Carboxylic acid sodium salt; DOPE-PEG-COOH; 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[carboxy(polyethylene glycol)]; Poly(oxy-1,2-ethanediyl), α-(carboxymethyl)-ω-[[(10R,21Z)-7-hydroxy-7-oxido-2,13-dioxo-10-[[(9Z)-1-oxo-9-octadecen-1-yl]oxy]-6,8,12-trioxa-3-aza-7-phosphatriacont-21-en-1-yl]oxy]-, sodium salt (1:1)
Purity >99%
Solubility Soluble in Chloroform, Methanol, Ammonium Hydroxide
Related CAS 2342575-86-2 (free base)
Shelf Life 1 Year
Storage Store at -20°C
Exact Mass 2774.667
Hygroscopic No
Light Sensitive No
Percent Composition C 56.67%, H 9.19%, N 0.50%, Na 0.83%, O 31.69%, P 1.12%

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PEGylation of Peptides and Proteins

PEGylation of Peptides
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