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DOPE-PEG-NH2 ammonium salt

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Category mPEG Phospholipids
Catalog NO. BPG-2999
Product Name DOPE-PEG-NH2 ammonium salt
CAS 2342575-85-1
Molecular Formula (C2H4O)nC44H83N2O10P.H3N
Molecular Weight 2786.489
DOPE-PEG-NH2 ammonium salt
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Description DOPE-PEG-NH2 ammonium salt features a terminal amine group on a PEGylated phosphatidylethanolamine backbone, providing a reactive platform for further chemical modification. The primary amine moiety enables facile coupling with activated esters, aldehydes, or carboxyl groups, facilitating the creation of diverse lipid conjugates. The DOPE anchor maintains membrane fluidity and curvature, while the PEG segment enhances solubility and biocompatibility. As an ammonium salt, it offers improved handling and aqueous dispersibility. DOPE-PEG-NH2 is frequently employed in customizable liposome construction, polymer grafting, and the generation of multifunctional lipid nanostructures with controlled surface chemistry.
Synonyms DOPE-PEG-Amine ammonium salt; DOPE-PEG-NH2; 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[amino(polyethylene glycol)]; Poly(oxy-1,2-ethanediyl), α-[(9R,20Z)-6-hydroxy-6-oxido-1,12-dioxo-9-[[(9Z)-1-oxo-9-octadecen-1-yl]oxy]-5,7,11-trioxa-2-aza-6-phospha-20-nonacosen-1-yl]-ω-(2-aminoethoxy)-, ammonium salt
Purity >99%
Solubility Soluble in Chloroform, Methanol, Ammonium Hydroxide
Related CAS 1429661-98-2 (free base)
Shelf Life 1 Year
Storage Store at -20°C
Exact Mass 2784.759
Hygroscopic No
Light Sensitive No
Percent Composition C 56.90%, H 9.48%, N 1.51%, O 31.00%, P 1.11%

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