Mal-PEG12-NHS ester
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| Category | Mal-PEGn-NHS ester |
| Catalog NO. | BPG-0365 |
| Product Name | Mal-PEG12-NHS ester |
| Molecular Formula | C35H58N2O18 |
| Molecular Weight | 794.85 |
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Product Information
| Description | Mal-PEG12-NHS ester is a non-cleavable ADC linker containing the Maleimide group. It can be used to prepare antibody conjugated drugs (ADCs). |
| Synonyms | 2,5-dioxopyrrolidin-1-yl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12,15,18,21,24,27,30,33,36-dodecaoxanonatriacontan-39-oate; 1-{39-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-39-oxo-3,6,9,12,15,18,21,24,27,30,33,36-dodecaoxanonatriacont-1-yl}-1H-pyrrole-2,5-dione |
| IUPAC Name | (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate |
| SMILES | C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN2C(=O)C=CC2=O |
| InChI | InChI=1S/C35H58N2O18/c38-31-1-2-32(39)36(31)6-8-44-10-12-46-14-16-48-18-20-50-22-24-52-26-28-54-30-29-53-27-25-51-23-21-49-19-17-47-15-13-45-11-9-43-7-5-35(42)55-37-33(40)3-4-34(37)41/h1-2H,3-30H2 |
| InChIKey | WYDVLWOHCQFWPD-UHFFFAOYSA-N |
| Boiling Point | 789.4±70.0°C at 760 mmHg |
| Purity | ≥95% |
| Density | 1.3±0.1 g/cm3 |
| Related CAS | 357277-60-2 (polymer) 1303508-68-0 (polymer) 1520853-90-0 (polymer) 1802486-72-1 (polymer) |
| Appearance | Pale Yellow or Colorless Oily Matter |
| Storage | Store at 2-8°C |
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PEGylation of Peptides
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Reduce the Immunogenicity of Peptide/Protein Drugs
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