Mal-PEG4-NHS
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| Category | Mal-PEGn-NHS ester |
| Catalog NO. | BPG-3588 |
| Product Name | Mal-PEG4-NHS |
| CAS | 1325208-25-0 |
| Molecular Formula | C19H26N2O10 |
| Molecular Weight | 442.42 |
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| Description | Mal-PEG4-NHS is a heterobifunctional ADC linker that combines maleimide and NHS ester functionalities, enabling thiol and amine conjugation. The PEG4 spacer enhances hydrophilicity and biocompatibility, ideal for stable antibody-drug conjugation. |
| Synonyms | Mal-PEG4-NHS ester; 2,5-dioxopyrrolidin-1-yl 1-(2,5-dioxo-2H-pyrrol-1(5H)-yl)-3,6,9,12-tetraoxapentadecan-15-oate; 4,7,10,13-Tetraoxapentadecanoic acid, 15-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 2,5-dioxo-1-pyrrolidinyl ester; 2,5-dioxopyrrolidin-1-yl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12-tetraoxapentadecan-15-oate; 1-{15-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl}-1H-pyrrole-2,5-dione; 1H-Pyrrole-2,5-dione, 1-[15-[(2,5-dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl]- |
| IUPAC Name | (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-(2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]ethoxy]ethoxy]propanoate |
| SMILES | C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCCN2C(=O)C=CC2=O |
| InChI | InChI=1S/C19H26N2O10/c22-15-1-2-16(23)20(15)6-8-28-10-12-30-14-13-29-11-9-27-7-5-19(26)31-21-17(24)3-4-18(21)25/h1-2H,3-14H2 |
| InChIKey | TUPOSLKVPPFQGR-UHFFFAOYSA-N |
| Boiling Point | 580.5±60.0°C (Predicted) |
| Purity | ≥98% |
| Density | 1.36±0.1 g/cm3 (Predicted) |
| Solubility | Soluble in DCM, DMSO |
| Related CAS | 357277-60-2 (polymer) 1303508-68-0 (polymer) 1520853-90-0 (polymer) 1802486-72-1 (polymer) |
| Appearance | Light Yellow Oily Matter |
| Storage | Store at 2-8°C under inert gas (nitrogen or argon) |
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BOC Sciences supplies a unique variety of PEG derivatives and functional PEG polymers. Our products offer the most diverse collection of reactivity, ready-to-use functionality, and molecular weight options that you will not find anywhere else.
PEGylation of Peptides
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Reduce the Immunogenicity of Peptide/Protein Drugs
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