Mal-PEG2-acid
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| Category | Mal-PEGn-acid |
| Catalog NO. | BPG-1843 |
| Product Name | Mal-PEG2-acid |
| CAS | 1374666-32-6 |
| Molecular Formula | C11H15NO6 |
| Molecular Weight | 257.24 |
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Product Information
| Description | Mal-PEG2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG2-acid can be conjugated to Tubulysin (HY-128914) and its derivative cytotoxic molecule. |
| Synonyms | Mal-PEG2-CH2CH2COOH; Maleimide-PEG2-CH2CH2COOH; Mal-PEG2-COOH; Mal-PEG2-propionic acid; 3-(2-(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy)ethoxy)propanoic acid; Propanoic acid, 3-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]- |
| IUPAC Name | 3-[2-[2-(2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]propanoic acid |
| SMILES | C1=CC(=O)N(C1=O)CCOCCOCCC(=O)O |
| InChI | InChI=1S/C11H15NO6/c13-9-1-2-10(14)12(9)4-6-18-8-7-17-5-3-11(15)16/h1-2H,3-8H2,(H,15,16) |
| InChIKey | TXMDOUPVKVGPIS-UHFFFAOYSA-N |
| Boiling Point | 455.7±35.0 °C at 760 mmHg |
| Flash Point | 229.4±25.9 °C |
| Purity | ≥95% |
| Density | 1.329±0.06 g/cm3 (Predicted) |
| Solubility | Soluble in DMSO (10 mm) |
| Related CAS | 357277-61-3 (polymer) 2422928-26-3 (polymer) |
| Appearance | White to Light Yellow Powder to Crystal |
| Shelf Life | 0-4°C for short term (days to weeks), or -20°C for long term (months). |
| Storage | Store at 2-8°C |
| Vapor Pressure | 0.0±2.4 mmHg at 25°C |
| LogP | -0.73 |
| Pictogram(s) | Irritant |
| Signal | Warning |
| Precautionary Statement Codes | P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 |
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