MC-PEG2-C2-NHS ester
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| Category | Small-molecule Heterobifunctional PEG |
| Catalog NO. | BPG-3585 |
| Product Name | MC-PEG2-C2-NHS ester |
| CAS | 1263044-56-9 |
| Molecular Formula | C21H29N3O9 |
| Molecular Weight | 467.47 |
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Product Information
| Description | MC-PEG2-C2-NHS ester is a non-cleavable 2-unit PEG linker that is used in the synthesis of antibody-conjugated drugs (ADCs). |
| Synonyms | 2,5-dioxopyrrolidin-1-yl 3-(2-(2-(6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamido)ethoxy)ethoxy)propanoate; 6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-[2-(2-{3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy}ethoxy)ethyl]hexanamide; 1H-Pyrrole-1-hexanamide, N-[2-[2-[3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy]ethoxy]ethyl]-2,5-dihydro-2,5-dioxo-; Propanoic acid, 3-[2-[2-[[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]amino]ethoxy]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester; 2,5-Dioxo-1-pyrrolidinyl 3-[2-[2-[[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]amino]ethoxy]ethoxy]propanoate |
| IUPAC Name | (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[6-(2,5-dioxopyrrol-1-yl)hexanoylamino]ethoxy]ethoxy]propanoate |
| SMILES | C1CC(=O)N(C1=O)OC(=O)CCOCCOCCNC(=O)CCCCCN2C(=O)C=CC2=O |
| InChI | InChI=1S/C21H29N3O9/c25-16(4-2-1-3-11-23-17(26)5-6-18(23)27)22-10-13-32-15-14-31-12-9-21(30)33-24-19(28)7-8-20(24)29/h5-6H,1-4,7-15H2,(H,22,25) |
| InChIKey | RKGUGSULMVQEIX-UHFFFAOYSA-N |
| Purity | ≥98% |
| Density | 1.33±0.1 g/cm3 |
| Solubility | Soluble in DMSO |
| Related CAS | 948595-09-3 (polymer) |
| Appearance | Soild powder |
| Storage | Store at 2-8°C |
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