m-PEG12-amine
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| Category | m-PEGn-amine |
| Catalog NO. | BPG-2345 |
| Product Name | m-PEG12-amine |
| CAS | 1977493-48-3 |
| Molecular Formula | C25H53NO12 |
| Molecular Weight | 559.69 |
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Product Information
| Description | m-PEG12-amine is a non-cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
| Synonyms | mPEG12-NH2; Methyl-PEG12-amine |
| IUPAC Name | 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanamine |
| SMILES | COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN |
| InChI | InChI=1S/C25H53NO12/c1-27-4-5-29-8-9-31-12-13-33-16-17-35-20-21-37-24-25-38-23-22-36-19-18-34-15-14-32-11-10-30-7-6-28-3-2-26/h2-26H2,1H3 |
| InChIKey | MSKSQCLPULZWNO-UHFFFAOYSA-N |
| Boiling Point | 583.6±45.0°C at 760 mmHg |
| Flash Point | 291.3±22.4 °C |
| Purity | >95% |
| Density | 1.073±0.06 g/cm3 |
| Solubility | Soluble in Water, DMSO, DCM, DMF |
| Related CAS | 80506-64-5 (polymer) 869718-87-6 (polymer) |
| Appearance | Colorless to light yellow |
| Shelf Life | 0-4°C for short term (days to weeks), or -20°C for long term (months). |
| Storage | Store at 2-8°C |
| Vapor Pressure | 0.0±1.6 mmHg at 25°C |
| LogP | -4.59 |
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BOC Sciences supplies a unique variety of PEG derivatives and functional PEG polymers. Our products offer the most diverse collection of reactivity, ready-to-use functionality, and molecular weight options that you will not find anywhere else.
PEGylation of Peptides
and Proteins
Reduce the Immunogenicity of Peptide/Protein Drugs
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APPLICATIONS
PEG linkers For Drug
Improved Circulation Half-Life
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