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mPEG8-amine

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Category m-PEGn-amine
Catalog NO. BPG-2059
Product Name mPEG8-amine
CAS 869718-81-0
Molecular Formula C17H37NO8
Molecular Weight 383.48
mPEG8-amine
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Product Information

Description mPEG8-amine features a long PEG chain with an amine terminus, ideal for ADC linker synthesis. Its extended PEG8 spacer improves bioconjugate solubility, reduces aggregation, and enhances circulation stability in targeted drug delivery systems.
Synonyms m-PEG8-amine; 2,5,8,11,14,17,20,23-Octaoxapentacosan-25-amine; mPEG8-NH2; 3,6,9,12,15,18,21,24-Octaoxapentacosan-1-amine; 3,6,9,12,15,18,21,24-octaoxa-pentacosylamine; methyl-PEG8-amine
IUPAC Name 2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanamine
SMILES COCCOCCOCCOCCOCCOCCOCCOCCN
InChI InChI=1S/C17H37NO8/c1-19-4-5-21-8-9-23-12-13-25-16-17-26-15-14-24-11-10-22-7-6-20-3-2-18/h2-18H2,1H3
InChIKey YXWBFPPGROXJLL-UHFFFAOYSA-N
Boiling Point 448.0±40.0°C (Predicted)
Flash Point 213.9°C
Purity ≥95%
Density 1.054±0.06 g/cm3 (Predicted)
Solubility Soluble in DMSO, Water
Related CAS 80506-64-5 (polymer) 869718-87-6 (polymer)
Appearance Pale Yellow Oily Matter
Storage Store at 2-8°C
Exact Mass 383.25191714
LogP 0.40800
Pictogram(s) Irritant
Signal Warning
Precautionary Statement Codes P264, P264+P265, P280, P302+P352, P305+P351+P338, P321, P332+P317, P337+P317, and P362+P364

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PEGylation of Peptides and Proteins

PEGylation of Peptides
and Proteins

Reduce the Immunogenicity of Peptide/Protein Drugs

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APPLICATIONS

PEG linkers For Drug

Improved Circulation Half-Life

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