mPEG6-NHS ester

Name: mPEG6-NHS ester
Brand: BOC Sciences
Rating: 5 (1 reviews)

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Category	Small-molecule Methoxy Linear PEG (mPEG)
Catalog NO.	BPG-2124
Product Name	mPEG6-NHS ester
CAS	1449390-12-8
Molecular Formula	C18H31NO10
Molecular Weight	421.44

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Description	mPEG6-NHS ester is a PEG linker with a reactive NHS ester group used for amine coupling in ADC synthesis. The PEG6 spacer increases hydrophilicity, ensuring stable payload conjugation and improved pharmacokinetic behavior of antibody-drug conjugates.
Synonyms	2,5-dioxopyrrolidin-1-yl 2,5,8,11,14,17-hexaoxaicosan-20-oate
IUPAC Name	(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]propanoate
SMILES	COCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O
InChI	InChI=1S/C18H31NO10/c1-23-6-7-25-10-11-27-14-15-28-13-12-26-9-8-24-5-4-18(22)29-19-16(20)2-3-17(19)21/h2-15H2,1H3
InChIKey	KIIPLYSZOISNAS-UHFFFAOYSA-N
Boiling Point	502.6±60.0 °C at 760 mmHg
Flash Point	257.8±32.9 °C
Purity	>98.0%
Density	1.2±0.1 g/cm3
Solubility	10 mm in DMSO
Appearance	Colorless Liquid
Shelf Life	0-4°C for short term (days to weeks), or -20°C for long term (months).
Storage	Store at -20 °C, keep in dry and avoid sunlight.
Vapor Pressure	0.0±1.3 mmHg at 25°C
LogP	-3.59

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BOC Sciences supplies a unique variety of PEG derivatives and functional PEG polymers. Our products offer the most diverse collection of reactivity, ready-to-use functionality, and molecular weight options that you will not find anywhere else.