Propargyl-PEG4-thiol
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
| Category | Small-molecule Heterobifunctional PEG |
| Catalog NO. | BPG-1829 |
| Product Name | Propargyl-PEG4-thiol |
| CAS | 1347750-80-4 |
| Molecular Formula | C11H20O4S |
| Molecular Weight | 248.34 |
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Product Information
| Description | Propargyl-PEG4-thiol is an alkyne-functionalized ADC linker with a terminal thiol for maleimide or disulfide chemistry. It enables flexible bioconjugation in antibody-drug conjugates, offering enhanced solubility, spacer length, and reduced steric hindrance. |
| Synonyms | Alkyne-PEG4-thiol;Propyne-PEG4-SH; 3,6,9,12-Tetraoxapentadec-14-yne-1-thiol |
| IUPAC Name | 2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]ethanethiol |
| SMILES | C#CCOCCOCCOCCOCCS |
| InChI | InChI=1S/C11H20O4S/c1-2-3-12-4-5-13-6-7-14-8-9-15-10-11-16/h1,16H,3-11H2 |
| InChIKey | QFVYBCQBSOIWFU-UHFFFAOYSA-N |
| Boiling Point | 332.9±37.0 °C at 760 mmHg |
| Flash Point | 155.1±26.5 °C |
| Purity | >98.0% |
| Density | 1.1±0.1 g/cm3 |
| Solubility | 10 mm in DMSO |
| Appearance | Colorless Liquid |
| Shelf Life | 0-4°C for short term (days to weeks), or -20°C for long term (months). |
| Storage | Store at -20 °C, keep in dry and avoid sunlight. |
| Vapor Pressure | 0.0±0.7 mmHg at 25°C |
| LogP | 0.09 |
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BOC Sciences supplies a unique variety of PEG derivatives and functional PEG polymers. Our products offer the most diverse collection of reactivity, ready-to-use functionality, and molecular weight options that you will not find anywhere else.
PEGylation of Peptides
and Proteins
Reduce the Immunogenicity of Peptide/Protein Drugs
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APPLICATIONS
PEG linkers For Drug
Improved Circulation Half-Life
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