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t-Boc-N-amido-PEG2-acetic acid

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Category Small-molecule Group Protected PEG
Catalog NO. BPG-1850
Product Name t-Boc-N-amido-PEG2-acetic acid
CAS 108466-89-3
Molecular Formula C11H21NO6
Molecular Weight 263.29
t-Boc-N-amido-PEG2-acetic acid
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Description t-Boc-N-amido-PEG2-acetic acid is a Boc-protected PEGylated acetic acid derivative incorporating a short ethylene glycol spacer. The PEG2 segment introduces flexibility and hydrophilic character into molecular constructs. The acetic acid functionality enables conjugation to PNA backbones or related linkers. This compound is applied in the synthesis of PNA monomers or conjugates with spacer-modified architectures.
Synonyms 2,2-Dimethyl-4-oxo-3,8,11-trioxa-5-azatridecan-13-oic acid; t-Boc-N-amido-PEG2-CH2CO2H; Boc-NH-PEG2-CH2COOH; Boc-8-amino-3,6-dioxaoctanoic acid; [2-[2-(Boc-amino)ethoxy]ethoxy]acetic acid; Boc-AEEA; Boc-O2Oc; Boc-Adoa; Boc-Ado; Boc-AEEA-OH; Boc-8-Adox-OH; 8-(t-Butoxycarbonyl)amino-3,6-dioxaoctanoic acid
IUPAC Name 2-[2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethoxy]ethoxy]acetic acid
SMILES CC(C)(C)OC(=O)NCCOCCOCC(=O)O
InChI InChI=1S/C11H21NO6/c1-11(2,3)18-10(15)12-4-5-16-6-7-17-8-9(13)14/h4-8H2,1-3H3,(H,12,15)(H,13,14)
InChIKey OMBVJVWVXRNDSL-UHFFFAOYSA-N
Boiling Point 631.4±45.0 °C at 760 mmHg
Melting Point 90-92 °C
Purity 98%
Density 1.3±0.1 g/cm3
Related CAS 560088-79-1 (DCHA salt)
Appearance White to Off-white Powder
Storage Store at -20 °C
LogP 0.83330
Pictogram(s) Irritant
Signal Warning
Precautionary Statement Codes P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

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