t-Boc-N-amido-PEG4-amine
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| Category | NHBoc-PEGn-amine |
| Catalog NO. | BPG-1980 |
| Product Name | t-Boc-N-amido-PEG4-amine |
| CAS | 811442-84-9 |
| Molecular Formula | C15H32N2O6 |
| Molecular Weight | 336.42 |
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Product Information
| Description | t-Boc-N-amido-PEG4-amine is a protected PEG linker with an amine functionality, useful in ADC synthesis. The Boc group ensures selective deprotection, enabling precise linker assembly, while PEG4 spacing improves solubility and flexibility of antibody-drug conjugates. |
| Synonyms | Boc-NH-PEG4-CH2CH2NH2; NHBoc-PEG4-amine; O-(2-Aminoethyl)-O'-[2-(Boc-amino)ethyl]triethylene Glycol; 16-Amino-5,8,11,14-tetraoxa-2-azahexadecanoic Acid 1,1-Dimethylethyl Ester; tert-Butyl (14-amino-3,6,9,12-tetraoxatetradecyl)carbamate; N1-Boc-3,6,9,12-tetraoxatetradecane-1,14-diamine; BocNH-PEG4-NH2; 5,8,11,14-Tetraoxa-2-azahexadecanoic acid, 16-amino-, 1,1-dimethylethyl ester |
| IUPAC Name | tert-butyl N-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethyl]carbamate |
| SMILES | CC(C)(C)OC(=O)NCCOCCOCCOCCOCCN |
| InChI | InChI=1S/C15H32N2O6/c1-15(2,3)23-14(18)17-5-7-20-9-11-22-13-12-21-10-8-19-6-4-16/h4-13,16H2,1-3H3,(H,17,18) |
| InChIKey | WCNWLERBLMBSOT-UHFFFAOYSA-N |
| Boiling Point | 443.9±40.0 °C at 760 mmHg |
| Purity | ≥95% |
| Density | 1.059±0.06 g/cm3 (Predicted) |
| Solubility | Soluble in DMSO (Slightly), Methanol (Slightly) |
| Related CAS | 890091-42-6 (polymer) 198227-38-2 (polymer) |
| Appearance | Pale Yellow or Colorless Oily Liquid |
| Storage | Store at 2-8°C, protect from light |
| Exact Mass | 336.22603674 |
| LogP | 1.62740 |
| Pictogram(s) | Corrosive, Irritant |
| Signal | Danger |
| Precautionary Statement Codes | P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P305+P354+P338, P317, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 |
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BOC Sciences supplies a unique variety of PEG derivatives and functional PEG polymers. Our products offer the most diverse collection of reactivity, ready-to-use functionality, and molecular weight options that you will not find anywhere else.
PEGylation of Peptides
and Proteins
Reduce the Immunogenicity of Peptide/Protein Drugs
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PEG linkers For Drug
Improved Circulation Half-Life
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