t-Boc-N-amido-PEG8-amine
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| Category | NHBoc-PEGn-amine |
| Catalog NO. | BPG-0565 |
| Product Name | t-Boc-N-amido-PEG8-amine |
| CAS | 1052207-59-6 |
| Molecular Formula | C23H48N2O10 |
| Molecular Weight | 512.64 |
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Product Information
| Description | t-Boc-N-amido-PEG8-amine is a cleavable 8-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). |
| Synonyms | BocNH-PEG8-CH2CH2NH2; NHBoc-PEG8-amine; Boc-NH-PEG8-NH2; Boc-N-amido-PEG8-NH2; tert-Butyl (26-amino-3,6,9,12,15,18,21,24-octaoxahexacosyl)carbamate; 5,8,11,14,17,20,23,26-Octaoxa-2-azaoctacosanoic acid, 28-amino-, 1,1-dimethylethyl ester; 2-Methyl-2-propanyl (26-amino-3,6,9,12,15,18,21,24-octaoxahexacos-1-yl)carbamate; Carbamic acid, N-(26-amino-3,6,9,12,15,18,21,24-octaoxahexacos-1-yl)-, 1,1-dimethylethyl ester |
| IUPAC Name | tert-butyl N-[2-[2-[2-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamate |
| SMILES | CC(C)(C)OC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCN |
| InChI | InChI=1S/C23H48N2O10/c1-23(2,3)35-22(26)25-5-7-28-9-11-30-13-15-32-17-19-34-21-20-33-18-16-31-14-12-29-10-8-27-6-4-24/h4-21,24H2,1-3H3,(H,25,26) |
| InChIKey | RJDFELJBUQILOQ-UHFFFAOYSA-N |
| Boiling Point | 579.4±50.0°C at 760 mmHg |
| Purity | ≥95% |
| Density | 1.1±0.1 g/cm3 |
| Solubility | Soluble in DCM, DMF, DMSO, Water |
| Related CAS | 890091-42-6 (polymer) 198227-38-2 (polymer) |
| Appearance | Pale Yellow or Colorless Oily Matter |
| Storage | Store at 2-8°C |
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BOC Sciences supplies a unique variety of PEG derivatives and functional PEG polymers. Our products offer the most diverse collection of reactivity, ready-to-use functionality, and molecular weight options that you will not find anywhere else.
PEGylation of Peptides
and Proteins
Reduce the Immunogenicity of Peptide/Protein Drugs
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APPLICATIONS
PEG linkers For Drug
Improved Circulation Half-Life
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