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Azido-PEG4-propionic acid

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Category Azido-PEGn-Acid
Catalog NO. BPG-1898
Product Name Azido-PEG4-propionic acid
CAS 1257063-35-6
Molecular Formula C11H21N3O6
Molecular Weight 291.30
Azido-PEG4-propionic acid
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Product Information

Description Azido-PEG4-propionic acid is a specialized heterobifunctional reagent featuring an azide group and a short polyethylene glycol (PEG) spacer linked to a propionic acid moiety. The azido functionality facilitates efficient click chemistry reactions, enabling site-specific conjugation to alkyne-containing molecules. The PEG4 spacer imparts enhanced aqueous solubility and reduces steric hindrance, which is beneficial in peptide modification and surface functionalization studies. Frequently utilized in bioconjugation, proteomics, and targeted delivery research, this compound supports precise molecular design and advanced chemical biology applications.
Synonyms Azido-PEG4-acid;N3-PEG4-COOH; Azido-PEG4-C2-acid; Azido-PEG4-Acid; N3-PEG4-CH2CH2COOH; 1-Azido-3,6,9,12-tetraoxapentadecan-15-oic acid; 15-Azido-4,7,10,13-tetraoxapentadecanoic acid
IUPAC Name 3-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]propanoic acid
SMILES C(COCCOCCOCCOCCN=[N+]=[N-])C(=O)O
InChI InChI=1S/C11H21N3O6/c12-14-13-2-4-18-6-8-20-10-9-19-7-5-17-3-1-11(15)16/h1-10H2,(H,15,16)
InChIKey BODPHGOBXPGJKO-UHFFFAOYSA-N
Purity ≥95%
Solubility Soluble in DMSO (10 mm)
Related CAS 1167575-20-3 (polymer)
Appearance Colorless to light orange to yellow clear liquid
Storage Store at 2-8°C
Exact Mass 291.14303540
LogP 0.29056
Pictogram(s) Irritant
Signal Warning
Precautionary Statement Codes P264, P264+P265, P280, P302+P352, P305+P351+P338, P321, P332+P317, P337+P317, and P362+P364

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PEGylation of Peptides and Proteins

PEGylation of Peptides
and Proteins

Reduce the Immunogenicity of Peptide/Protein Drugs

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