NHPI-PEG2-C2-NHS ester

Name: NHPI-PEG2-C2-NHS ester
Brand: BOC Sciences
Rating: 5 (1 reviews)

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Category	NHPI-PEGn-C2-NHS ester
Catalog NO.	BPG-0587
Product Name	NHPI-PEG2-C2-NHS ester
CAS	2101206-31-7
Molecular Formula	C19H20N2O9
Molecular Weight	420.37

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Custom Synthesis
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Description	NHPI-PEG2-C2-NHS ester is a highly reactive ADC linker intermediate with PEG2 spacer and N-hydroxyphthalimide activation. It facilitates selective payload attachment, enhancing antibody-drug conjugate synthesis efficiency and linker stability.
Synonyms	Phthalimidooxy-PEG2-NHS ester; 2,5-Dioxopyrrolidin-1-yl 3-(2-(2-(1,3-dioxoisoindolin-2-yloxy)ethoxy)ethoxy)propanoate; Propanoic acid, 3-[2-[2-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)oxy]ethoxy]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester; 2-[2-(2-{3-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy}ethoxy)ethoxy]-1H-isoindole-1,3(2H)-dione; 1H-Isoindole-1,3(2H)-dione, 2-[2-[2-[3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy]ethoxy]ethoxy]-
IUPAC Name	(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-(1,3-dioxoisoindol-2-yl)oxyethoxy]ethoxy]propanoate
SMILES	C1CC(=O)N(C1=O)OC(=O)CCOCCOCCON2C(=O)C3=CC=CC=C3C2=O
InChI	InChI=1S/C19H20N2O9/c22-15-5-6-16(23)20(15)30-17(24)7-8-27-9-10-28-11-12-29-21-18(25)13-3-1-2-4-14(13)19(21)26/h1-4H,5-12H2
InChIKey	UXABBPKGOKMLNT-UHFFFAOYSA-N
Boiling Point	580.0±60.0°C at 760 mmHg
Purity	≥95%
Density	1.5±0.1 g/cm3
Solubility	Soluble in DMSO
Storage	Store at 2-8°C

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