NHPI-PEG4-C2-NHS ester
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| Category | NHPI-PEGn-C2-NHS ester |
| Catalog NO. | BPG-3600 |
| Product Name | NHPI-PEG4-C2-NHS ester |
| CAS | 1415328-95-8 |
| Molecular Formula | C23H28N2O11 |
| Molecular Weight | 508.48 |
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Product Information
| Description | NHPI-PEG4-C2-NHS ester is a cleavable PEG linker containing NHS ester and N-hydroxyphthalimide groups, enabling controlled release of payloads in ADCs. The PEG4 spacer offers enhanced solubility and biocompatibility in targeted drug delivery applications. |
| Synonyms | 2,5-dioxopyrrolidin-1-yl 1-(1,3-dioxoisoindolin-2-yloxy)-3,6,9,12-tetraoxapentadecan-15-oate; Phthalimidooxy-PEG4-NHS ester; 4,7,10,13-Tetraoxapentadecanoic acid acid, 15-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)oxy]-, 2,5-dioxo-1-pyrrolidinyl ester; 1H-Isoindole-1,3(2H)-dione, 2-[[15-[(2,5-dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl]oxy]-; 2-({15-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl}oxy)-1H-isoindole-1,3(2H)-dione |
| IUPAC Name | (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-(1,3-dioxoisoindol-2-yl)oxyethoxy]ethoxy]ethoxy]ethoxy]propanoate |
| SMILES | C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCCON2C(=O)C3=CC=CC=C3C2=O |
| InChI | InChI=1S/C23H28N2O11/c26-19-5-6-20(27)24(19)36-21(28)7-8-31-9-10-32-11-12-33-13-14-34-15-16-35-25-22(29)17-3-1-2-4-18(17)23(25)30/h1-4H,5-16H2 |
| InChIKey | HLAGLPXQSIDIDX-UHFFFAOYSA-N |
| Boiling Point | 638.5±65.0°C at 760 mmHg |
| Purity | 98% |
| Density | 1.4±0.1 g/cm3 |
| Solubility | Soluble in DMSO |
| Appearance | Pale Yellow or Colorless Oily Matter |
| Storage | Store at 2-8°C |
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