NHPI-PEG3-C2-NHS ester
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| Category | NHPI-PEGn-C2-NHS ester |
| Catalog NO. | BPG-0586 |
| Product Name | NHPI-PEG3-C2-NHS ester |
| CAS | 2101206-14-6 |
| Molecular Formula | C21H24N2O10 |
| Molecular Weight | 464.42 |
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Product Information
| Description | NHPI-PEG3-C2-NHS ester extends PEG2 to PEG3 spacer length, optimizing linker flexibility and conjugation kinetics. It serves as an efficient ADC linker for stable payload attachment and enhanced antibody-drug conjugate pharmacodynamics. |
| Synonyms | Phthalimidooxy-PEG3-NHS ester; Propanoic acid, 3-[2-[2-[2-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)oxy]ethoxy]ethoxy]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester; 2-{2-[2-(2-{3-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy}ethoxy)ethoxy]ethoxy}-1H-isoindole-1,3(2H)-dione; 1H-Isoindole-1,3(2H)-dione, 2-[2-[2-[2-[3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]-; 2,5-Dioxopyrrolidin-1-yl 3-(2-(2-(2-(1,3-dioxoisoindolin-2-yloxy)ethoxy)ethoxy)ethoxy)propanoate |
| IUPAC Name | (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-(1,3-dioxoisoindol-2-yl)oxyethoxy]ethoxy]ethoxy]propanoate |
| SMILES | C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCON2C(=O)C3=CC=CC=C3C2=O |
| InChI | InChI=1S/C21H24N2O10/c24-17-5-6-18(25)22(17)33-19(26)7-8-29-9-10-30-11-12-31-13-14-32-23-20(27)15-3-1-2-4-16(15)21(23)28/h1-4H,5-14H2 |
| InChIKey | OWAQXTSIBSTPOX-UHFFFAOYSA-N |
| Boiling Point | 612.6±65.0°C at 760 mmHg |
| Purity | ≥95% |
| Density | 1.4±0.1 g/cm3 |
| Solubility | Soluble in DMSO |
| Storage | Store at 2-8°C |
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BOC Sciences supplies a unique variety of PEG derivatives and functional PEG polymers. Our products offer the most diverse collection of reactivity, ready-to-use functionality, and molecular weight options that you will not find anywhere else.
PEGylation of Peptides
and Proteins
Reduce the Immunogenicity of Peptide/Protein Drugs
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PEG linkers For Drug
Improved Circulation Half-Life
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