Bis(NHS)PEG5
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| Category | Bis-PEGn-NHS ester |
| Catalog NO. | BPG-2300 |
| Product Name | Bis(NHS)PEG5 |
| CAS | 756526-03-1 |
| Molecular Formula | C22H32N2O13 |
| Molecular Weight | 532.50 |
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Product Information
| Description | Bis(NHS)PEG5 is a non-cleavable 5-unit PEG linker that can be used to synthesize antibody-conjugated drugs (ADCs). |
| Synonyms | Bis-PEG5-NHS ester; Bis(2,5-dioxopyrrolidin-1-yl) 4,7,10,13,16-pentaoxanonadecane-1,19-dioate; NHS-PEG5-NHS; Bis-dPEG(R)5-NHS ester; Bis(2,5-dioxopyrrolidin-1-yl) 4,7,10,13,16-pentaoxanonadecanedioate; Bis(3-PEG4)propionic acid N-hydroxysuccinimide diester; 1,1'-[(1,19-Dioxo-4,7,10,13,16-pentaoxanonadecane-1,19-diyl)bis(oxy)]di(2,5-pyrrolidinedione); 2,5-Pyrrolidinedione, 1,1'-[(1,19-dioxo-4,7,10,13,16-pentaoxanonadecane-1,19-diyl)bis(oxy)]bis-; α,ω-disuccinimidyl tetraethylene glycol |
| IUPAC Name | (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[3-(2,5-dioxopyrrolidin-1-yl)oxy-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate |
| SMILES | C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCCOCCC(=O)ON2C(=O)CCC2=O |
| InChI | InChI=1S/C22H32N2O13/c25-17-1-2-18(26)23(17)36-21(29)5-7-31-9-11-33-13-15-35-16-14-34-12-10-32-8-6-22(30)37-24-19(27)3-4-20(24)28/h1-16H2 |
| InChIKey | FTYUGLBWKRXQBD-UHFFFAOYSA-N |
| Boiling Point | 632.5±65.0°C at 760 mmHg |
| Purity | 98% |
| Density | 1.4±0.1 g/cm3 |
| Solubility | Soluble in DCM, DMF, DMSO |
| Related CAS | 123502-57-8 (polymer) |
| Appearance | Colorless to Yellow Clear Liquid to Cloudy Liquid |
| Storage | Store at 2-8°C |
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BOC Sciences supplies a unique variety of PEG derivatives and functional PEG polymers. Our products offer the most diverse collection of reactivity, ready-to-use functionality, and molecular weight options that you will not find anywhere else.
PEGylation of Peptides
and Proteins
Reduce the Immunogenicity of Peptide/Protein Drugs
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PEG linkers For Drug
Improved Circulation Half-Life
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