Bis-PEG13-NHS ester
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| Category | Bis-PEGn-NHS ester |
| Catalog NO. | BPG-1241 |
| Product Name | Bis-PEG13-NHS ester |
| CAS | 2221949-00-2 |
| Molecular Formula | C38H64N2O21 |
| Molecular Weight | 884.92 |
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Product Information
| Description | Bis-PEG13-NHS ester is a non-cleavable 13-unit PEG linker that can be used to synthesize antibody-conjugated drugs (ADCs). |
| Synonyms | 4,7,10,13,16,19,22,25,28,31,34,37,40-Tridecaoxatritetracontanedioic acid, 1,43-bis(2,5-dioxo-1-pyrrolidinyl) ester; Bis-dPEG13-NHS ester; Di-NHS Ester-PEG13; NHS-PEG13-NHS; Bis-dPEG(R)13-NHS ester; 1,1'-[(1,43-Dioxo-4,7,10,13,16,19,22,25,28,31,34,37,40-tridecaoxatritetracontane-1,43-diyl)bis(oxy)]di(2,5-pyrrolidinedione); 2,5-Pyrrolidinedione, 1,1'-[(1,43-dioxo-4,7,10,13,16,19,22,25,28,31,34,37,40-tridecaoxatritetracontane-1,43-diyl)bis(oxy)]bis- |
| IUPAC Name | (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[3-(2,5-dioxopyrrolidin-1-yl)oxy-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate |
| SMILES | C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON2C(=O)CCC2=O |
| InChI | InChI=1S/C38H64N2O21/c41-33-1-2-34(42)39(33)60-37(45)5-7-47-9-11-49-13-15-51-17-19-53-21-23-55-25-27-57-29-31-59-32-30-58-28-26-56-24-22-54-20-18-52-16-14-50-12-10-48-8-6-38(46)61-40-35(43)3-4-36(40)44/h1-32H2 |
| InChIKey | OVDFFVRBNAHLOH-UHFFFAOYSA-N |
| Boiling Point | 833.0±75.0°C (Predicted) |
| Purity | ≥95% |
| Density | 1.27±0.1 g/cm3 (Predicted) |
| Solubility | 10 mm in DMSO |
| Related CAS | 123502-57-8 (polymer) |
| Appearance | Pale Yellow or Colorless Oily Matter |
| Shelf Life | 0-4°C for short term (days to weeks), or -20°C for long term (months). |
| Storage | Store at 2-8°C |
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PEGylation of Peptides
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Reduce the Immunogenicity of Peptide/Protein Drugs
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