Bis-PEG2-NHS Ester
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| Category | Bis-PEGn-NHS ester |
| Catalog NO. | BPG-3565 |
| Product Name | Bis-PEG2-NHS Ester |
| CAS | 65869-63-8 |
| Molecular Formula | C16H20N2O10 |
| Molecular Weight | 400.34 |
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Product Information
| Description | Bis-PEG2-NHS Ester is a homobifunctional ADC linker with two NHS groups for crosslinking amine-containing biomolecules. The PEG2 spacer minimizes steric hindrance and improves aqueous solubility, supporting multivalent conjugation. |
| Synonyms | Bis(2,5-dioxopyrrolidin-1-yl) 3,3'-(ethane-1,2-diylbis(oxy))dipropionate; Bis-PEG2-NHS; 2,5-Pyrrolidinedione, 1,1'-[1,2-ethanediylbis[oxy(1-oxo-3,1-propanediyl)oxy]]bis-; 1,1'-{1,2-Ethanediylbis[oxy(1-oxo-3,1-propanediyl)oxy]}di(2,5-pyrrolidinedione) |
| IUPAC Name | (2,5-dioxopyrrolidin-1-yl) 3-[2-[3-(2,5-dioxopyrrolidin-1-yl)oxy-3-oxopropoxy]ethoxy]propanoate |
| SMILES | C1CC(=O)N(C1=O)OC(=O)CCOCCOCCC(=O)ON2C(=O)CCC2=O |
| InChI | InChI=1S/C16H20N2O10/c19-11-1-2-12(20)17(11)27-15(23)5-7-25-9-10-26-8-6-16(24)28-18-13(21)3-4-14(18)22/h1-10H2 |
| InChIKey | SORMJGWNAXHOFC-UHFFFAOYSA-N |
| Boiling Point | 547.2±60.0°C (Predicted) |
| Purity | ≥98% |
| Density | 1.46±0.1 g/cm3 (Predicted) |
| Solubility | Soluble in DMSO |
| Related CAS | 123502-57-8 (polymer) |
| Appearance | White Solid |
| Storage | Store at 2-8°C |
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PEGylation of Peptides
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